N (%) |
311 (48) |
170 (26) |
173 (26) |
Gross infarcts, n (%) |
109 (35) |
83 (49) |
85 (49) |
Microscopic infarcts, n (%) |
97 (31) |
65 (38) |
72 (41) |
Atherosclerosis, n (%) |
|
|
|
Severe |
21 (7) |
9 (5) |
12 (7) |
Moderate |
53 (17) |
38 (22) |
34 (20) |
Mild |
166 (53) |
79 (47) |
92 (53) |
Arteriolosclerosis, n (%) |
|
|
|
Severe |
18 (6) |
14 (8) |
12 (7) |
Moderate |
69 (22) |
36 (21) |
34 (20) |
Mild |
113 (36) |
73 (43) |
76 (44) |
Cerebral amyloid angiopathy, n (%) |
|
|
|
Severe |
37 (12) |
12 (7) |
26 (15) |
Moderate |
74 (24) |
41 (24) |
42 (24) |
Mild |
137 (44) |
85 (50) |
69 (40) |
NIA Reagan (Likelihood of AD), n (%) |
|
|
|
High or intermediate |
218 (70) |
124 (73) |
121 (70) |
Amyloid plaques, mean (SD) |
0.86 (0.66) |
0.84 (0.63) |
0.85 (0.62) |
Neurofibrilary tangles, mean (SD) |
0.80 (0.87) |
0.78 (0.89) |
0.70 (0.84) |
Lewy Bodies, n (%) |
90 (29) |
45 (27) |
54 (31) |
Hippocampal sclerosis, n (%) |
46 (15) |
18 (11) |
13 (8) |
TDP-43 pathology, n (%) |
|
|
|
Inclusions in amygdala, entorhinal cortex or hippocampus CA1, and neocortex |
60 (19) |
25 (15) |
22 (13) |
Inclusions in amygdala, and entorhinal cortex or hippocampus CA1 |
67 (22) |
33 (19) |
37 (21) |
Inclusions in amygdala only |
51 (16) |
40 (24) |
25 (14) |