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Radioactive HPLC profiles (A) of 99mTc(CO)3-NOTA-GGNle-CycMSHhex (NOTA) and 99mTc(CO)3-NODAGA-GGNle-CycMSHhex (NODAGA). The retention time of 99mTc(CO)3-NOTA-GGNle-CycMSHhex and 99mTc(CO)3-NODAGA-GGNle-CycMSHhex was 15.6 and 12.8 min, respectively. Specific binding (B) of 99mTc(CO)3-NOTA-GGNle-CycMSHhex and 99mTc(CO)3-NODAGA-GGNle-CycMSHhex on B16/F10 melanoma cells with (white) and without (black) peptide blockade.
