Figure 1.

Fabrication of MC. (A) Schematic of MC fabrication. Ace-DEX scaffolds are electrospun and then homogenized to fragment the fibers into MC. Representative scanning electron micrograph of electrospun scaffold. Scale bar is 5 μm. (B) Scanning electron micrographs of small, medium, and large MC at different magnifications. Scale bar is 25 μm. Width (C) and length (D) measurements taken by ImageJ. Data represented as mean ± standard error of the mean. (E) Injectability of MC through a 26 G needle. Increments of 0.2 mL were pushed through the needle, degraded, and normalized to 0.2 mL of that volume pipetted to represent the intended MC dose. (F) Table containing electrospinning fabrication parameters (polymer concentration and flow rate) and resulting MC dimensions (length, width, and aspect ratio). Aspect ratio calculated by the average length divided by width. Data represented as mean ± standard deviation. MC: microconfetti. ****p < 0.0001.