Table 1.
Domains and measures evaluated in the CGA before treatment.
| Domain with measure | Item | n | % | Median | Range |
|---|---|---|---|---|---|
| Functional status | |||||
| KPS (0–100) | 90 | 30 | 65.2 | ||
| 80 | 13 | 28.3 | |||
| 70 | 3 | 6.5 | |||
| ADL (Barthel index; 0–100)* | Independent: score 100 | 24 | 58.5 | 100 | 50–100 |
| Minimally dependent: score 75–95 | 13 | 31.7 | |||
| Partially dependent: score 50–70 | 4 | 9.8 | |||
| IADL (Lawton's; 0–5/8)* | Independent: score 8 (female) or 5 (male) | 25 | 61.0 | 7 (female) | 5–8 (female) |
| Dependent: score < 8 (female) or 5 (male) | 16 | 39.0 | 5 (male) | 2–5 (male) | |
| Comorbidity | |||||
| CCI (0–37) | 0 | 33 | 71.7 | ||
| 1 | 12 | 26.1 | |||
| 2 | 1 | 2.2 | |||
| Cognitive status | |||||
| MMSE (0–30)* | Normal cognition: score 24–30 | 31 | 75.6 | 28 | 21–30 |
| Mild cognitive decline: score 18–23 | 10 | 24.4 | |||
| Psychological status | |||||
| GDS-5 (0–5)* | Not at risk for depression: score 0 | 21 | 51.2 | 0 | 0–5 |
| Mild depression: score 1–2 | 9 | 22.0 | |||
| Severe depression: score 3–5 | 11 | 26.8 | |||
| Nutritional status | |||||
| BMI (kg/m2) | Underweight < 18.5 | 5 | 10.9 | 23.1 | 17–37 |
| Normal weight: 18.5–23.9 | 29 | 63.0 | |||
| Overweight: 24–29.9 | 10 | 21.8 | |||
| Obesity: ≥ 30 | 2 | 4.3 | |||
| MNA-SF (0–14)* | Normal nutritional status: score 12–14 | 12 | 29.3 | 10 | 6–14 |
| Risk of malnutrition: ≤ 11 | 29 | 70.7 | |||
| MNA (0-−0)† | Normal nutritional status: score 24–30 | 10 | 34.5 | 23 | 11–28 |
| Risk of malnutrition: 17–23.5 | 16 | 55.2 | |||
| Malnutrition: < 17 | 3 | 10.3 | |||
| Social support | |||||
| MOS-SSS (20–100)* | NA | 84 | 53–100 |
*
Calculated using the number of patients with completed questionnaires (n = 41).
†
Calculated using the number of patients with a positive MNA screening test (n = 29).
Abbreviations: ADL, activities of daily life; BMI, body-mass index; CCI, Charlson comorbidity index; CGA, comprehensive geriatric assessment; GDS-5, 5-item geriatric depression scale; IADL, instrumental activities of daily living; KPS, Karnofsky performance status; MMSE, Mini Mental State Examination; MNA, Mini Nutritional Assessment; MNA-SF, MNA-short form; MOS-SSS, Medical Outcomes Study—social support survey.