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. 2020 Aug 26;177(19):4416–4432. doi: 10.1111/bph.15182

FIGURE 2.

FIGURE 2

Ibrutinib treatment reduces inflammatory cell recruitment in the liver of mice fed a HFD. (a) Relative gene expression of CXCL1, CCL2, and CCL5 were assessed by qPCR and normalized to 18S. Relative gene expression of CD68 (b) and BTK (c) were assessed by qPCR and normalized to 18S in the liver. (d) Correlation of relative gene expression of CD68 to BTK in the liver. Correlation was calculated by linear regression including 95% confidence intervals. (e) Immune cell infiltration was assessed by H&E staining. Inset images are 4× digital zoom. Data shown are individual values with means ± SEM. * P < 0.05, significantly different from HFD + Veh; one‐way ANOVA with Bonferroni post hoc test