Table 4.
Univariate and multivariate analyses of the impact of plasma FABP1 and FABP2 level on diabetic nephropathy
| Factor | Tertiles of FABP1 | |||
|---|---|---|---|---|
| T1 (95% CI) | T2 (95%CI) | T3 (95%CI) | p value | |
| All subjects | ||||
| No. of cases/reference | 15/74 | 38/51 | 41/49 | <0.0001 |
| Cut off FABP1 concentration (ng/mL) | <25.4 | 25.4-38.1 | >38.1 | |
| Univariate | 1.00 | 3.68 (1.86-7.55) | 4.13 (2.10-8.46) | <0.0001 |
| Multivariatea | 1.00 | 3.47 (1.59-7.88) | 4.22 (1.85-10.03) | 0.001 |
| Tertiles of FABP2 | ||||
| Factor | T1 (95% CI) | T2 (95%CI) | T3 (95%CI) | p value |
| All subjects | ||||
| No. of cases/reference | 24/64 | 33/59 | 37/51 | 0.012 |
| Cut off FABP2 concentration (ng/mL) | <1.52 | 1.52-2.32 | >2.32 | |
| Univariate | 1.00 | 1.49 (0.79-2.83) | 1.94 (1.03-3.67) | 0.039 |
| Multivariatea | 1.00 | 1.34 (0.65-2.79) | 1.62 (1.50-11.81) | 0.041 |
Values shown are cut-offs of plasma FABP1 and FABP2 levels of all subjects, and odds ratios (ORs) with 95% confidence intervals (CIs). aAdjusted for age, sex, body mass index, systolic blood pressure, diastolic blood pressure, fasting glucose, total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, and smoking. FABP, fatty acid-binding protein.