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. 2020 Jul 29;17(14):2113–2124. doi: 10.7150/ijms.46259

Table 4.

Pathological characteristics of individuals stratified by quartiles of baseline serum transferrin levels

Characteristics Serum transferrin (g/L)
Q1 (n = 26) Q2 (n = 26) Q3 (n = 33) Q4 (n = 26) P value
≤1.15 g/L 1.15-1.38 g/L 1.38-1.65 g/L ≥1.65 g/L
RPS classification, n (%) 0.01
I 0 (0) 1 (3.8) 1 (3.1) 2 (7.4)
IIa 0 (0) 1 (3.8) 5 (15.6) 3 (11.1)
IIb 0 (0) 2 (7.7) 4 (12.5) 3 (11.1)
III 20 (76.9) 18 (69.2) 16 (50.0) 11 (40.7)
IV 6 (23.1) 4 (15.4) 6 (18.8) 8 (29.6)
IFTA, n (%) 0.51
0 0 (0) 2 (7.7) 0 (0) 0 (0)
1 8 (30.8) 10 (38.5) 18 (56.3) 10 (37.0)
2 13 (50.0) 10 (38.5) 7 (21.9) 10 (37.0)
3 5 (19.2) 4 (15.4) 7 (21.9) 7 (25.9)
Interstitial inflammation, n (%) 0.48
0 0 (0) 1 (3.8) 1 (3.1) 0 (0)
1 18 (69.2) 18 (69.2) 27 (84.4) 17 (63.0)
2 8 (30.8) 7 (26.9) 4 (12.5) 10 (37.0)
Arteriosclerosis, n (%) 0.17
0 1 (3.8) 3 (11.5) 3 (9.4) 2 (7.4)
1 10 (38.5) 12 (46.2) 20 (62.5) 12 (44.4)
2 15 (57.7) 9 (34.6) 9 (28.1) 13 (48.1)
Arteriolar hyalinosis, n (%) 0.50
0 0 (0) 3 (11.5) 1 (3.1) 2 (7.4)
1 6 (23.1) 10 (38.5) 8 (25.0) 6 (22.2)
2 20 (76.9) 13 (50.0) 23 (71.9) 19 (70.4)

Data are presented as percent for categorical variables. Defined by RPS Diabetic Nephropathy Classification.

Abbreviations: ESRD, end-stage renal disease; RPS, Renal Pathology Society; IFTA, interstitial fibrosis and tubular atrophy.