Table 2.

Gene Ontology term enrichment analysis of DEGs in LC/SP cells of MM.

Expression	Category	ID	Term	Count	PValue
	BP	GO:0045087	innate immune response	28	3.13E-09
	BP	GO:0006954	inflammatory response	25	2.07E-08
	BP	GO:0006955	immune response	20	8.02E-05
	BP	GO:0006691	leukotriene metabolic process	5	8.69E-05
	BP	GO:0030593	neutrophil chemotaxis	8	1.07E-04
	CC	GO:0005886	plasma membrane	122	1.23E-11
	CC	GO:0016021	integral component of membrane	131	5.17E-08
UP-DEGs	CC	GO:0005615	extracellular space	48	1.22E-06
	CC	GO:0042581	specific granule	6	1.47E-06
	CC	GO:0005887	integral component of plasma membrane	46	2.27E-05
	MF	GO:0030246	carbohydrate binding	12	4.29E-04
	MF	GO:0005509	calcium ion binding	24	1.91E-03
	MF	GO:0050544	arachidonic acid binding	3	2.63E-03
	MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4	4.76E-03
	MF	GO:0005536	glucose binding	3	1.36E-02
	BP	GO:0006782	protoporphyrinogen IX biosynthetic process	5	1.81E-05
	BP	GO:0006783	heme biosynthetic process	6	4.80E-05
	BP	GO:0030218	erythrocyte differentiation	7	1.31E-04
	BP	GO:0006779	porphyrin-containing compound biosynthetic process	4	4.09E-04
	BP	GO:0008283	cell proliferation	19	4.20E-04
	CC	GO:0070062	extracellular exosome	84	2.77E-05
	CC	GO:0005833	hemoglobin complex	5	5.86E-05
DOWN-DEGs	CC	GO:0014731	spectrin-associated cytoskeleton	4	3.66E-04
	CC	GO:0015629	actin cytoskeleton	13	1.08E-03
	CC	GO:0005739	mitochondrion	42	1.84E-03
	MF	GO:0034987	immunoglobulin receptor binding	5	1.51E-03
	MF	GO:0005344	oxygen transporter activity	4	2.28E-03
	MF	GO:0004029	aldehyde dehydrogenase (NAD) activity	4	4.07E-03
	MF	GO:0051015	actin filament binding	9	4.36E-03
	MF	GO:0004064	arylesterase activity	3	5.39E-03