Table 4.
The top 5 significantly enriched GO terms and corresponding gene information in module analysis
| Modules | GO-ID | P-value | corr P-value | x | Description | Genes in test set |
|---|---|---|---|---|---|---|
| 6952 | 2.31E-16 | 2.51E-13 | 20 | defense response | ORM1|CRISP3|ITGB2|HP|CYBB|RAB27A|CXCL1|FPR2|LILRB2|PLD1|CFP|CLEC4D|CLEC5A|C3AR1|LCN2|OLR1|PTX3|PGLYRP1|CAMP|LTF | |
| 2376 | 6.99E-13 | 3.80E-10 | 20 | immune system process | ITGAM|ARG1|CRISP3|ITGB2|CYBB|RAB27A|CXCL1|LILRB2|CFP|MMP9|FCAR|CHIT1|BST1|CLEC4D|C3AR1|LCN2|PTX3|CEACAM8|PGLYRP1|LTF | |
| module 1 | 6955 | 1.24E-11 | 4.49E-09 | 16 | immune response | ARG1|CRISP3|CYBB|RAB27A|CXCL1|LILRB2|CFP|FCAR|CHIT1|BST1|CLEC4D|LCN2|PTX3|CEACAM8|PGLYRP1|LTF |
| 5576 | 3.52E-10 | 9.56E-08 | 24 | extracellular region | ORM1|ARG1|CRISP3|HP|CXCL1|RETN|OLFM4|MMP8|CFP|MMP9|FCAR|CHIT1|TCN1|CEACAM1|SLPI|LCN2|OLR1|CHI3L1|PTX3|CEACAM8|FOLR3|PGLYRP1|CAMP|LTF | |
| 30246 | 6.48E-09 | 1.38E-06 | 11 | carbohydrate binding | CHIT1|ITGAM|CLEC4D|CLEC12A|ARG1|CLEC5A|OLR1|CHI3L1|PTX3|PGLYRP1|LTF | |
| 22403 | 2.21E-18 | 1.13E-15 | 14 | cell cycle phase | PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5|CDKN3 | |
| 7049 | 3.54E-18 | 1.13E-15 | 16 | cell cycle | PLK1|HJURP|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5|CDKN3|E2F8 | |
| module 2 | 87 | 6.92E-18 | 1.48E-15 | 12 | M phase of mitotic cell cycle | CDC20|CCNB2|ASPM|KIFC1|PLK1|CDK1|PBK|CDCA8|OIP5|CDC25C|NDC80|DLGAP5 |
| 279 | 9.72E-18 | 1.56E-15 | 13 | M phase | PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5 | |
| 278 | 2.74E-17 | 3.51E-15 | 13 | mitotic cell cycle | PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|OIP5|DLGAP5|CDKN3 | |
| 7186 | 1.94E-08 | 8.23E-06 | 7 | G-protein coupled receptor protein signaling pathway | CXCL12|CXCR1|CXCR2|PNOC|NMU|ADCY4|APLNR | |
| 42330 | 8.82E-08 | 1.25E-05 | 5 | taxis | CXCL6|CXCL12|CXCR1|CCL5|CXCR2 | |
| module 3 | 6935 | 8.82E-08 | 1.25E-05 | 5 | chemotaxis | CXCL6|CXCL12|CXCR1|CCL5|CXCR2 |
| 7610 | 4.59E-07 | 4.18E-05 | 6 | behavior | CXCL6|CXCL12|CXCR1|CCL5|CXCR2|NMU | |
| 4918 | 4.93E-07 | 4.18E-05 | 2 | interleukin-8 receptor activity | CXCR1|CXCR2 |