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. 2020 Jul 25;17(14):2063–2076. doi: 10.7150/ijms.48244

Table 4.

The top 5 significantly enriched GO terms and corresponding gene information in module analysis

Modules GO-ID P-value corr P-value x Description Genes in test set
6952 2.31E-16 2.51E-13 20 defense response ORM1|CRISP3|ITGB2|HP|CYBB|RAB27A|CXCL1|FPR2|LILRB2|PLD1|CFP|CLEC4D|CLEC5A|C3AR1|LCN2|OLR1|PTX3|PGLYRP1|CAMP|LTF
2376 6.99E-13 3.80E-10 20 immune system process ITGAM|ARG1|CRISP3|ITGB2|CYBB|RAB27A|CXCL1|LILRB2|CFP|MMP9|FCAR|CHIT1|BST1|CLEC4D|C3AR1|LCN2|PTX3|CEACAM8|PGLYRP1|LTF
module 1 6955 1.24E-11 4.49E-09 16 immune response ARG1|CRISP3|CYBB|RAB27A|CXCL1|LILRB2|CFP|FCAR|CHIT1|BST1|CLEC4D|LCN2|PTX3|CEACAM8|PGLYRP1|LTF
5576 3.52E-10 9.56E-08 24 extracellular region ORM1|ARG1|CRISP3|HP|CXCL1|RETN|OLFM4|MMP8|CFP|MMP9|FCAR|CHIT1|TCN1|CEACAM1|SLPI|LCN2|OLR1|CHI3L1|PTX3|CEACAM8|FOLR3|PGLYRP1|CAMP|LTF
30246 6.48E-09 1.38E-06 11 carbohydrate binding CHIT1|ITGAM|CLEC4D|CLEC12A|ARG1|CLEC5A|OLR1|CHI3L1|PTX3|PGLYRP1|LTF
22403 2.21E-18 1.13E-15 14 cell cycle phase PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5|CDKN3
7049 3.54E-18 1.13E-15 16 cell cycle PLK1|HJURP|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5|CDKN3|E2F8
module 2 87 6.92E-18 1.48E-15 12 M phase of mitotic cell cycle CDC20|CCNB2|ASPM|KIFC1|PLK1|CDK1|PBK|CDCA8|OIP5|CDC25C|NDC80|DLGAP5
279 9.72E-18 1.56E-15 13 M phase PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|RAD54L|OIP5|DLGAP5
278 2.74E-17 3.51E-15 13 mitotic cell cycle PLK1|CDCA8|CDC25C|NDC80|CDC20|CCNB2|ASPM|KIFC1|CDK1|PBK|OIP5|DLGAP5|CDKN3
7186 1.94E-08 8.23E-06 7 G-protein coupled receptor protein signaling pathway CXCL12|CXCR1|CXCR2|PNOC|NMU|ADCY4|APLNR
42330 8.82E-08 1.25E-05 5 taxis CXCL6|CXCL12|CXCR1|CCL5|CXCR2
module 3 6935 8.82E-08 1.25E-05 5 chemotaxis CXCL6|CXCL12|CXCR1|CCL5|CXCR2
7610 4.59E-07 4.18E-05 6 behavior CXCL6|CXCL12|CXCR1|CCL5|CXCR2|NMU
4918 4.93E-07 4.18E-05 2 interleukin-8 receptor activity CXCR1|CXCR2