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. 2020 Aug 28;10:1664. doi: 10.3389/fonc.2020.01664

TABLE 1.

Characteristics of lung cancer patients with brain metastases.

Characteristics Small cell carcinoma (N = 13) Adenocarcinoma (N = 58) Squamous cell carcinoma (N = 9) p-value
Age (years) 67.08 ± 9.32 65.78 ± 10.74 70.11 ± 8.46 0.61
Sex 0.05
Male 12 (92.3%) 21 (36.2%) 1 (11.1%)
Female 1 (7.7%) 37 (63.8%) 8 (88.9%)
Smoking history 0.01
Yes 9 (75%) 24 (43.6%) 8 (88.8%)
No 3 (25%) 31 (56.4%) 1 (11.2%)
RPA 0.01
1 0 (0%) 0 (0%) 1 (11.1%)
2 8 (72.7%) 49 (90.7%) 5 (55.5%)
3 3 (27.3%) 5 (9.3%) 3 (33.4%)
Number of BMs 107 432 23
Number of BMs per patient 8.23 ± 11.00 7.45 ± 7.41 2.56 ± 2.07 0.13
BM volume (mm3) 544.36 ± 2767.97 350.86 ± 1795.51 4097.30 ± 15793.24 0.04

RPA, recursive partitioning analysis, BM, brain metastasis.