Table 1.
Characteristics of study subjects.
| Characteristics | Dengue (n = 172) | DWS (n = 107) | P value |
|---|---|---|---|
| Age (years) | 31 (14–81) | 31 (13–68) | NS |
| Gender | NS | ||
| Male n (%) | 82 (47.7) | 48 (44.9) | |
| Female n (%) | 90 (52.3) | 59 (55.1) | |
| DENV NS1 | NS | ||
| Positive n (%) | 153 (89.0) | 93 (86.9) | |
| Negative n (%) | 16 (9.3) | 10 (9.3) | |
| Undetermined n (%) | 3 (1.7) | 4 (3.7) | |
| DENV specific IgM | NS | ||
| Positive n (%) | 29 (16.9) | 27 (25.2) | |
| Negative n (%) | 138 (80.2) | 75 (70.1) | |
| Undetermined n (%) | 5 (2.9) | 5 (4.7) | |
| DENV specific IgG | 0.024 | ||
| Positive n (%) | 30 (17.4) | 31 (29) | |
| Negative n (%) | 137 (79.7) | 71 (66.4) | |
| Undetermined n (%) | 5 (2.9) | 5 (4.7) | |
| DENV serotype | |||
| DENV-1 n (%) | 45 (26.2) | 20 (18.7) | Reference |
| DENV-2 n (%) | 8 (4.6) | 13 (12.1) | 0.019 |
| DENV-1 and -2 n (%) | 1 (0.6) | 1 (0.9) | NS |
| Undetermined n (%) | 118 (68.6) | 69 (64.5) | |
| DENV Viremia (1/Ct × 100) | 3 (2–6)a | 3.1 (2–5)b | NS |
| Day of illness at hospital admission | 5 (1–13) | 5 (1–12) | NS |
| Day of illness | 9 (4–20) | 10 (6–16) | 0.001 |
| Bleeding | < 0.001 | ||
| Yes n (%) | 138 (80.2) | 46 (43) | |
| No n (%) | 34 (19.8) | 61 (57) | |
| Liver function test | |||
| AST (IU/ml) | 61.3 (18–369.2) | 108.3 (20.5–2,322) | < 0.001 |
| ALT (IU/ml) | 39 (8–301) | 73.8 (8.6–992.3) | < 0.001 |
| Blood count test | |||
| RBC (× 103/ml) | 4.6 (2.8–6.81) | 4.75 (2.88–7.17) | 0.048 |
| WBC (× 106/ml) | 3.39 (1–14.6) | 3.38 (1.19–17.29) | NS |
| PLT (× 103/ml) | 86.5 (3.2–316) | 60 (8–1,100) | < 0.001 |
| HCT (%) | 40 (27–53) | 40.7 (24–52) | NS |
Data presented as median (min–max).
DENV dengue virus; DWS dengue with warning signs; NS1 non-structural antigen 1; AST, ALT aspartate and alanine amino transferase; WBC white blood cells; RBC red blood cells; PLT platelets; HCT haematocrit; IU international unit; NS not significant; NA not applicable.
aDone in 65 samples.
bDone in 35 samples.