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Aortic endothelium gene (mRNA) changes in response to treatments.
| Treatment | Total gene changes | Down-regulated | Up-regulated | miR-92a-3p | miR-489-3p | ||||
|---|---|---|---|---|---|---|---|---|---|
| MMU predicted | Percent up-regulated | Human conserved | MMU predicted | Percent up-regulated | Human conserved | ||||
| HDL | 348 | 223 | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
| HDL + LNA-92a | 996 | 595 | 401 | 66 | 16.46 | 36 | n/a | n/a | n/a |
| HDL + LNA-489 | 404 | 120 | 284 | n/a | n/a | n/a | 73 | 25.70 | 28 |
| HDL + LNA-92a + LNA-489 | 242 | 132 | 109 | 14 | 12.84 | 7 | 20 | 18.35 | 4 |
