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. 2020 Aug 28;8:821. doi: 10.3389/fcell.2020.00821

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Copyright © 2020 Svandova, Anthwal, Tucker and Matalova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Disappearance of Meckel’s cartilage during development. Murine skeletal elements stained with alizarin red (bone) and alcian blue (cartilage) at stages: E15 (A), 16 (B), 19 (C), P1 (D,D₁), P4 (E,E₁), P7 (F,F₁). In figures (D,E,F) MC has been dissected away from the surrounding tissues, in figures (D₁,E₁,F₁) MC remains in situ surrounded by the cranial skeletal elements of the ear and jaw. Gonial bone (GB), incus (I), malleus (M), Meckel’s cartilage (MC), tympanic ring (TR). Taken from skeletal preps available in Svandova lab.