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. 2020 Apr 7;108(3):596–605. doi: 10.1002/cpt.1817

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© 2020 The Authors Clinical Pharmacology & Therapeutics published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Kaplan‐Meier survival curves for progression‐free survival are plotted for (a) overall population with at least 6 months of follow‐up, (b) those receiving clinical trial therapy and routine clinical practice therapy, (c) those receiving biomarker‐directed therapy and non‐biomarker‐directed therapy. CI, confidence interval; CNS, central nervous system; CUP, carcinoma of unknown primary; FDA, US Food and Drug Administration; M. MENINGIOMA, malignant meningioma; PFS, progression‐free survival; PNS, peripheral nervous system.