Table 1.
Overview of studies reporting children with PIMS-TS.
| Population | Location | Number of children in study | Number of settings | Eligibility | Date of publication | |
|---|---|---|---|---|---|---|
| Riphagen et al. (4) | Children with hyperinflammatory shock | London, UK | 8 | 1 | Admitted to PICU | May 6th 2020 |
| Verdoni et al. (5) | Children with Kawasaki-like disease | Bergamo, Italy | 10 | 1 | Admitted to the general pediatric unit | May 13th 2020 |
| Belhadjer et al. (6) | Children with acute heart failure in MIS-C | France, Switzerland | 35 | 14 | Admitted to PICU | May 17th 2020 |
| Chiotos et al. (7) | Children with MIS-C | Philadelphia, US | 6 | 1 | Admitted to PICU | May 28th 2020 |
| Grimaud et al. (8) | Acute myocarditis and multisystem inflammatory emerging disease in critically ill children | Paris, France | 20 | 4 | Admitted to PICU | June 1st 2020 |
| Toubiana et al. (9) | Children with Kawasaki-like multisystem inflammatory syndrome | Paris, France | 21 | 1 | Admitted to general pediatric ward | June 3rd 2020 |
| Miller et al. (10) | Children with MIS-C | New York, US | 44 | 1 | Admitted to hospital | June 4th 2020 |
| Whittaker et al. (11) | Children with PIMS-TS | United Kingdom | 58 | 8 | Admitted to hospital | June 8th 2020 |
| Cheung et al. (12) | Children with MIS-C | New York, US | 17 | 1 | Admitted to hospital | June 8th 2020 |
| Capone et al. (13) | Children with MIS-C | New York, US | 33 | 1 | Admitted to hospital | June 10th 2020 |
| Pouletty et al. (14) | Children with PIMS-TS mimicking Kawasaki disease (Kawa-COVID-19) | Paris, France | 16 | 7 | Admitted to hospital | June 11th 2020 |
| Ramcharan et al. (15) | Children with PIMS-TS | Birmingham, UK | 15 | 1 | Admitted to hospital | June 12th 2020 |
| Kaushik et al. (16) | Children with MIS-C | New York, US | 33 | 3 | Admitted to PICU | June 14th 2020 |
| Riollano-Cruz et al. (17) | Children with MIS-C | New York, US | 15 | 1 | Admitted to hospital | June 25th 2020 |
| Hameed et al. (18) | Children with PIMS-TS | London, UK | 35 | 1 | Admitted to hospital | June 25th 2020 |
| Feldstein et al. (19) | Children with MIS-C | US | 186a | 53 | Admitted to hospital | June 29th 2020 |
| Dufort et al. (20) | Children with MIS-C | New York, US | 99b | 106 | Admitted to hospital | June 29th 2020 |
Overview of articles describing cases of PIMS-TS, SARS-CoV-2 related Kawasaki-like disease, or MIS-C [per 29-06-2020]; only articles with 5 or more cases included.
Search strategy: using MIS-C, PIMS-TS and Kawasaki Disease as search terms in Medline search, age range: 0–<21 years, from April 1st to June 29th 2020; only English articles were included; only peer reviewed and published articles were included, pre-print manuscripts were excluded.
MISC, Multisystem Inflammatory Syndrome in Children; PICU, Pediatric Intensive Care Unit; PIMS-TS, Pediatric Inflammatory Multisystem Syndrome-temporally associated with SARS-CoV-2.
Feldstein et al. (19) excluded cases in the cohort described by Dufort et al. (20) (n = 27), but included cases reported by Chiotos et al. (7) (n = 6) and Waltuch et al. (21) (n = 4). Feldstein et al. (19): 186 cases meeting the case definition included out of 234 reported cases.
Dufort et al. (20): details of 99 confirmed or suspected cases via Public Health reporting registry included, out of 191 potential reported cases.