Fig. 5.

Expression of Gprk2 transgene in ellipsoid body neurons rescues ethanol (EtOH) sensitivity in Gprk2 mutant flies. (A–C) Loss of righting reflex (LORRt_1/2) was used to measure the level of EtOH sensitivity in flies. Three ellipsoid body neuron Gal4 drivers, 5.30 (A), ruslan (B), and 4.67 (C), were used to target the expression of Gprk2 in gprk2^KO mutants. Open bars, Gal4 or UAS transgene alone in gprk2^KO homozygous background; cyan bars, Gal4 and UAS transgene in gprk2^KO homozygous background; black bars, gprk2^KO heterozygous or wild‐type (CS) background. n = 10‐20. Mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 according to the 1‐way ANOVA with Bonferroni post hoc test.