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. 2019 Dec 23;11(1):51–71. doi: 10.1039/c9md00442d

Table 1. List of BP-based FDA approved drugs.

Name Structure Approval date (company) Treatment
Alendronate (Fosamax) graphic file with name c9md00442d-u1.jpg 11/24/1999 (Merck Research Laboratories) Osteogenesis imperfecta in pediatric patients (age >4)
Bone manifestations of Gaucher disease
Paget's disease
Glucocorticoid-induced osteoporosis
Osteoporosis
Risedronate (Actonel) graphic file with name c9md00442d-u2.jpg 3/27/1998 (Procter and Gamble Pharmaceuticals) Osteogenesis imperfecta
Ibandronate (Boniva) graphic file with name c9md00442d-u3.jpg 5/16/2003 (Hoffmann-La Roche Inc.) Osteoporosis in post-menopausal women
Pamidronate (Aredia) graphic file with name c9md00442d-u4.jpg 9/22/1998 (Novartis) Osteoporosis
Hypercalcemia
Etidronate (Didronel) graphic file with name c9md00442d-u5.jpg 4/20/1987 (MGI Pharma Inc.) Osteoporosis
Paget's disease
Tiludronate (Skelid) graphic file with name c9md00442d-u6.jpg 3/7/1997 (Sanofi Aventis US) Paget's disease
Zoledronate (Zometa, Reclast) graphic file with name c9md00442d-u7.jpg 2/22/2002 (Novartis) Tumor-induced hypercalcemia
Hypercalcemia of malignancy