Figure 4.
Effects of hesperidin on the Glo-1 activity (A), protein levels (B), and messenger RNA (mRNA) (C) levels in the amygdala and hippocampus of control rats (Cont), streptozotocin (STZ)-induced diabetic rats (DM), diabetic rats treated with hesperidin at low and high (50, 150 mg/kg) doses, and diabetic rats treated with the Nrf2 activator tert-butylhydroquinone (TBHQ) (25 mg/kg). The results are presented as the mean ± S.E.M., n = 7 [activity and messenger RNA (mRNA)], n = 6 (protein). *p < 0.05, **p < 0.01, vs. Cont group; #p < 0.05, ##p < 0.01, vs. DM group.