TABLE 2.

Key regulated factor of OS-related IRGs in LSCC patients.

Key TFs	Description	Regulated genes	P-value	FDR
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	FLT4, ICAM1, BMP2, FGF8, AMH	6.04E-05	0.000218
NFKB1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	FLT4, AMH, ICAM1, BMP2, FGF8	6.23E-05	0.000218
SP1	Sp1 transcription factor	ACVRL1, ICAM1, EDNRB, HGF, RETN	0.00049	0.00114
VDR	Vitamin D (1,25- dihydroxyvitamin D3) receptor	AMH, PTH	0.00164	0.00287
FOS	FBJ murine osteosarcoma viral oncogene homolog	SLC10A2, NTS	0.003	0.0042
PPARG	Peroxisome proliferator-activated receptor gamma	RETN, ICAM1	0.004	0.00466
STAT3	Signal transducer and activator of transcription 3 (acute-phase response factor)	HGF, ICAM1	0.0175	0.0175