Table 5.
Effect of prenatal exposure to VOC and NOx on selected measures of pulmonary function (resistance and reactance) (hPa.s.L−1) by age of follow up and during total period of study in preschool children from Morelos, Mexico.
| Pollutants | Resistance | Reactance | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rrs6 | Rrs8 | Rrs10 | Xrs6 | Xrs8 | Xrs10 | |||||||
| βa | p-value | βa | p-value | βa | p-value | βa | p-value | βa | p-value | βa | p-value | |
| 36 monthsb | ||||||||||||
| Xylene | −15.5 | 0.422 | −16.1 | 0.337 | −20.1 | 0.207 | 1.30 | 0.930 | 1.40 | 0.927 | 1.22 | 0.933 |
| NO2 | −0.018 | 0.491 | −0.015 | 0.179 | −0.013 | 0.191 | 0.003 | 0.780 | 0.007 | 0.448 | 0.007 | 0.414 |
| 48 monthsb | ||||||||||||
| Xylene | 20.8 | 0.070* | 25.4 | 0.025* | 20.3 | 0.064* | −9.33 | 0.199 | −12.6 | 0.089* | −11.7 | 0.177 |
| NO2 | 0.016 | 0.011* | 0.014 | 0.022* | 0.014 | 0.024* | −0.005 | 0.177 | −0.006 | 0.131 | −0.006 | 0.127 |
| 60 monthsb | ||||||||||||
| Xylene | 1.12 | 0.928 | −3.56 | 0.779 | −9.41 | 0.427 | −21.0 | 0.012* | −24.5 | 0.012* | −19.6 | 0.032* |
| NO2 | 0.008 | 0.300 | 0.004 | 0.568 | 0.003 | 0.654 | −0.010 | 0.045* | −0.010 | 0.089* | −0.008 | 0.139 |
| Follow upc | ||||||||||||
| Benzene | 26.99 | 0.704 | −40.89 | 0.551 | −50.60 | 0.427 | −13.23 | 0.789 | −13.70 | 0.798 | 1.61 | 0.975 |
| Toluene | −1.26 | 0.927 | 1.26 | 0.925 | 1.92 | 0.878 | −3.05 | 0.751 | −3.42 | 0.744 | −2.85 | 0.776 |
| Xylene | 9.48 | 0.304 | 9.08 | 0.303 | 4.37 | 0.593 | −11.40 | 0.074* | −11.91 | 0.083* | −10.14 | 0.124 |
| NO2 | 0.011 | 0.050* | 0.011 | 0.209 | 0.011 | 0.193 | −0.011 | 0.101 | −0.014 | 0.228 | −0.013 | 0.260 |
All model adjusted for age, age 2, height, sex, supplementation group, passive smoking and maternal history of atopy.
Lineal regression models.
Lineal mixed effects models.
.05 ≤ P ≤.08.