Table 4.

Results of patient-reported outcomes—Patient Global Impression of Improvement (PGI-I)

Timepoint PGI-I response		Oestrogen	No treatment	Relative risk (95% CI)‡
6 weeks		n=42	n=42
1=very much better	N (%)	22 (52%)	14 (33%)
2=much better	N (%)	16 (38%)	18 (43%)
3=a little better	N (%)	4 (10%)	8 (19%)
4=no change	N (%)	0 (-)	2 (5%)
5=a little worse	N (%)	0 (-)	0 (-)
6=much worse	N (%)	0 (-)	0 (-)
7=very much worse	N (%)	0 (-)	0 (-)
Better score*	N (%)	42 (100%)	40 (95%)	1.05 (0.98 to 1.12)
Worse score†	N (%)	0 (-)	2 (5%)
6 months		n=38	n=41
1=very much better	N (%)	13 (34%)	18 (44%)
2=much better	N (%)	16 (42%)	17 (41%)
3=a little better	N (%)	4 (11%)	5 (12%)
4=no change	N (%)	3 (8%)	0 (-)
5=a little worse	N (%)	2 (5%)	1 (2%)
6=much worse	N (%)	0 (-)	0 (-)
7=very much worse	N (%)	0 (-)	0 (-)
Better score*	N (%)	33 (87%)	40 (98%)	0.89 (0.78 to 1.02)
Worse score†	N (%)	5 (13%)	1 (2%)
12 months		n=37	n=42
1=very much better	N (%)	14 (38%)	17 (40%)
2=much better	N (%)	15 (41%)	17 (40%)
3=a little better	N (%)	3 (8%)	4 (10%)
4=no change	N (%)	4 (11%)	2 (5%)
5=a little worse	N (%)	1 (3%)	0 (-)
6=much worse	N (%)	0 (-)	2 (5%)
7=very much worse	N (%)	0 (-)	0 (-)
Better score*	N (%)	32 (86%)	38 (90%)	0.96 (0.81 to 1.12)
Worse score†	N (%)	5 (14%)	4 (10%)

*Better score is derived from scores 1 (very much better) to 3 (a little better).

†Worse score is derived from scores 4 (no change) to 7 (very much worse).

‡>1 indicates better with oestrogen.