Table 1.
Dose escalation scheme | ||
Period | Dose level | Dose |
Day 1–day 7 | 1* | 2 x/day 40 mg |
Day 8–day 14 | 2* | 2 x/day 80 mg |
Day 15–day of surgery or biopsy | 3* | 3 x/day 80 mg |
Tapering off scheme after surgery/biopsy | ||
Period | Dose | |
Day 1–day 7 | 2 x/day 80 mg | |
Day 8–day 14 | 2 x/day 40 mg |
*All patients start on day 1 with dose level 1.