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. Author manuscript; available in PMC: 2020 Sep 11.
Published in final edited form as: Cancer Immunol Res. 2019 Nov 26;8(1):131–145. doi: 10.1158/2326-6066.CIR-19-0315

Figure 1.

Figure 1

The K14HPV16/H2b mouse model. A) Schematic of the HPV16 transgene in K14HPV16/H2b mice, showing the human keratin 14 gene transcriptional regulatory region and the early region genes of HPV16. B) Timeline (in months) of cervical cancer development in K14HPV16/H2b mice. C) Representative histologic section of the cervix of a K14HPV16/H2b mouse (left) bearing squamous cell carcinoma (right). D) Representative flow cytometry analysis of H2Db, H2Kb, H2Kq and H2Dq/Lq expression on CD45+ cells in the blood of C57BL/6, FVBN and K14HPV16/H2b mice.