TABLE 4.
The multivariate analysis of factors associated with PFS and OS in overall included patients.
Variables | N | Progression-free survival |
Overall survival |
||||
HR | 95% CI | P | HR | 95% CI | P | ||
BMI | 0.071 | ||||||
<24 kg/m2 | 164 | 1 | |||||
≥24 kg/m2 | 92 | 2.538 | 0.924–6.968 | ||||
Comorbidities | 0.174 | 0.011 | |||||
0 | 213 | 1 | 1 | ||||
1 | 34 | 0.931 | 0.207–4.193 | 1.174 | 0.139–9.886 | ||
≥2 | 9 | 4.614 | 0.901–23.624 | 14.230 | 2.463–82.206 | ||
Adjuvant treatment | 0.097 | ||||||
No | 155 | 1 | |||||
Yes | 101 | 3.333 | 0.806–13.794 | ||||
Parametrial involvement | 0.220 | ||||||
No | 250 | 1 | |||||
Yes | 6 | 3.852 | 0.446–33.259 | ||||
Cervical stromal invasion depth | 0.508 | ||||||
<1/3 | 152 | 1 | |||||
≥1/3, <2/3 | 81 | 1.945 | 0.635–5.956 | ||||
≥2/3 | 23 | 1.540 | 0.336–7.069 | ||||
Tumor mass size | 0.085 | ||||||
≤2 cm | 175 | 1 | |||||
>2 cm | 81 | 2.605 | 0.877–7.731 | ||||
Operation approach | |||||||
ARH | 84 | 1 | 0.122 | 1 | 0.578 | ||
LRH | 172 | 0.449 | 0.162–1.239 | 0.650 | 0.143–2.961 |
ARH, abdominal radical hysterectomy; LRH, laparoscopic radical hysterectomy; BMI, body mass index.