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. 2020 Aug 28;11:1305. doi: 10.3389/fphar.2020.01305

Figure 2.

Figure 2

Change in body weight and survival after chronic injection of CYP at either 40 or 75 mg/kg dose. Rats received three intraperitoneal injections of saline (n = 12) at 5 ml/kg or CYP at either 40 (n = 24) or 75 (n = 12) mg/kg, on days 0, 3, and 6. (A) Body weight of CYP-injected rats were recorded over 17 days. Results were expressed as percentage of body weight of saline rats recorded at each time-point. Data represent mean values ± SEM. ***p < 0.001 (two-way RM ANOVA). (B) Kaplan-Meyer survival curves for rats chronically treated with either 40 or 75 mg/kg dose of CYP. **p = 0.0089 (Log-rank test).