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. 2020 Sep 8;8:e9848. doi: 10.7717/peerj.9848

Figure 6. Validate the negative relationship between hub genes and lung function in GSE47460 dataset.

Figure 6

(A–C) The relationship between expression levels of IL6, SERPINE1, SOCS3 and the Dlco% predicted of patients with IPF. Spearman correlation coefficients between Dlco% predicted and expression levels of IL6, SERPINE1, SOCS3 were −0.32 (p = 0.003), −0.41 (p < 0.001), and −0.46 (p < 0.001), respectively. (D–F) The relationship between expression levels of IL6, SERPINE1, SOCS3 and the FVC% predicted of patients with IPF. Spearman correlation coefficients between FVC% predicted and expression levels of IL6, SERPINE1, SOCS3 were −0.29 (p = 0.007), −0.33 (p = 0.002),and −0.27 (p = 0.012), respectively.