Table 4. GS and MM of 32 candidate hub genes in red module.
SGRQ score | FVC% predicted | Dlco% predicted | ||||||
---|---|---|---|---|---|---|---|---|
Gene | GS | P-value | GS | P-value | GS | P-value | MM | P-value |
NAMPT | 0.36 | 4.34E−04 | −0.47 | 2.90E−06 | −0.45 | 8.02E−06 | 0.92 | 6.27E−38 |
GADD45B | 0.32 | 1.98E−03 | −0.31 | 2.75E−03 | −0.30 | 3.47E−03 | 0.89 | 4.89E−32 |
THBS1 | 0.39 | 1.62E−04 | −0.51 | 1.83E−07 | −0.50 | 5.65E−07 | 0.88 | 3.46E−31 |
FOSL2 | 0.28 | 6.70E−03 | −0.42 | 3.77E−05 | −0.38 | 1.96E−04 | 0.88 | 2.49E−30 |
MYC | 0.24 | 2.47E−02 | −0.38 | 1.79E−04 | −0.32 | 1.85E−03 | 0.87 | 2.99E−29 |
ITPKC | 0.24 | 2.17E−02 | −0.33 | 1.28E−03 | −0.30 | 4.06E−03 | 0.86 | 5.16E−28 |
MT2A | 0.28 | 7.17E−03 | −0.44 | 1.55E−05 | −0.33 | 1.41E−03 | 0.86 | 1.12E−27 |
NNMT | 0.32 | 1.70E−03 | −0.44 | 1.07E−05 | −0.36 | 4.28E−04 | 0.86 | 1.59E−27 |
IL6 | 0.23 | 2.90E−02 | −0.31 | 2.38E−03 | −0.32 | 1.97E−03 | 0.86 | 1.96E−27 |
ERRFI1 | 0.29 | 4.82E−03 | −0.38 | 2.04E−04 | −0.38 | 2.27E−04 | 0.85 | 5.48E−27 |
SERPINE1 | 0.44 | 1.31E−05 | −0.52 | 1.03E−07 | −0.44 | 1.27E−05 | 0.85 | 2.54E−26 |
NFIL3 | 0.39 | 1.30E−04 | −0.47 | 2.04E−06 | −0.46 | 4.48E−06 | 0.85 | 4.49E−26 |
ITPRIP | 0.29 | 4.77E−03 | −0.27 | 1.11E−02 | −0.27 | 1.01E−02 | 0.85 | 5.69E−26 |
PPP1R15B | 0.24 | 2.06E−02 | −0.31 | 3.14E−03 | −0.29 | 5.05E−03 | 0.84 | 6.93E−26 |
SOCS3 | 0.28 | 6.45E−03 | −0.27 | 8.37E−03 | −0.30 | 4.31E−03 | 0.84 | 7.13E−26 |
SLC19A2 | 0.29 | 5.37E−03 | −0.41 | 5.63E−05 | −0.35 | 6.25E−04 | 0.84 | 1.44E−25 |
ADAMTS4 | 0.38 | 2.01E−04 | −0.39 | 1.09E−04 | −0.45 | 8.18E−06 | 0.84 | 1.61E−25 |
ZFP36 | 0.29 | 5.28E−03 | −0.34 | 8.46E−04 | −0.23 | 2.76E−02 | 0.84 | 2.86E−25 |
ADAMTS1 | 0.28 | 6.54E−03 | −0.31 | 3.16E−03 | −0.32 | 1.76E−03 | 0.83 | 4.31E−24 |
PHLDA1 | 0.38 | 2.37E−04 | −0.47 | 2.38E−06 | −0.46 | 5.78E−06 | 0.82 | 9.88E−24 |
SLC2A3 | 0.28 | 6.77E−03 | −0.32 | 1.99E−03 | −0.36 | 4.59E−04 | 0.82 | 1.25E−23 |
MT1M | 0.24 | 2.38E−02 | −0.34 | 9.14E−04 | −0.26 | 1.47E−02 | 0.82 | 2.04E−23 |
MT1JP | 0.26 | 1.31E−02 | −0.39 | 1.38E−04 | −0.34 | 9.10E−04 | 0.82 | 2.75E−23 |
MT1A | 0.20 | 5.13E−02 | −0.40 | 9.79E−05 | −0.29 | 5.49E−03 | 0.82 | 3.22E−23 |
C11orf96 | 0.41 | 5.88E−05 | −0.36 | 5.21E−04 | −0.36 | 5.22E−04 | 0.82 | 6.40E−23 |
CDKN1A | 0.33 | 1.65E−03 | −0.36 | 3.92E−04 | −0.32 | 1.74E−03 | 0.82 | 6.53E−23 |
CEBPD | 0.27 | 9.00E−03 | −0.32 | 1.72E−03 | −0.28 | 6.34E−03 | 0.81 | 1.88E−22 |
APOLD1 | 0.28 | 6.42E−03 | −0.23 | 2.85E−02 | −0.26 | 1.37E−02 | 0.81 | 2.85E−22 |
SLCO4A1 | 0.32 | 2.26E−03 | −0.45 | 7.30E−06 | −0.40 | 1.00E−04 | 0.81 | 3.52E−22 |
RNF122 | 0.23 | 2.58E−02 | −0.28 | 7.49E−03 | −0.25 | 1.56E−02 | 0.81 | 4.16E−22 |
PELI1 | 0.25 | 1.89E−02 | −0.25 | 1.49E−02 | −0.32 | 1.87E−03 | 0.80 | 9.76E−22 |
SOCS2 | 0.26 | 1.15E−02 | −0.24 | 2.09E−02 | −0.32 | 1.89E−03 | 0.80 | 9.89E−22 |