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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Hypertension. 2020 Aug 24;76(4):1113–1123. doi: 10.1161/HYPERTENSIONAHA.119.14013

Figure 2. CypA overexpression increases EC-derived SM22α positive cells in vivo, indicating EndMT.

Figure 2.

A-B, Representative immunofluoresence images for SM22α (red), GFP (green) and DAPI (blue) of different size pulmonary arteries in lung sections from WT;mTmG (n=5) and Cdh5-CypA;mTmG mice (n=8). Scale bar, 25μm(A) and 50μm(B). C-D, Representative immunofluoresence images for SM22α (red), GFP (green) and DAPI (blue) of alveoli in lung sections from WT;mTmG and Cdh5-CypA;mTmG mice. Scale bar, 25μm. E-F, Quantification of the total number of SM22α+ cells per field (E) and the percentage of SM22α+ cells that were GFP+ in all SM22α+ cells (F) as shown in C-D. Data are mean±SEM. *P<0.05.