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. Author manuscript; available in PMC: 2021 Feb 4.
Published in final edited form as: Biochemistry. 2019 Dec 31;59(4):541–551. doi: 10.1021/acs.biochem.9b00822

Figure 1.

Figure 1.

(A) Cartoon showing inhibitors of programmed death-ligand 1 (PD-L1) or programmed cell death protein 1 (PD-1) can block the interaction between the two proteins, reactivating the immune response; (B) Structure of macrocyclic peptide (macrocycle), an inhibitor of PD-1/PD-L1 protein-protein interaction.