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. Author manuscript; available in PMC: 2021 Apr 6.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 Jan 16;59(15):5880–5889. doi: 10.1002/anie.201907662

Figure 10.

Figure 10.

Structures of selected SuFEx reagents for ABPP. 16 enables kinase profiling by reacting with lysine residues.17 labels tyrosine residue in the enzyme DcPS. 18 is the first reagent used to label serine proteases. 19 reacts with serine, generating a product that loses water.