TABLE 1.

Differential metabolite statistics

Analysis mode, comparison group	Significantly different metabolite species (VIP ≥ 1, FC ≥ 1.2, or FC ≤ 0.83, q < 0.05)
	Positive ion mode	Trend	Negative ion mode	Trend
E2 vs E1	486	219↑	271	149↑
		267↓		122↓
E3 vs E1	1,577	605↑	656	252↑
		972↓		404↓
E3 vs E2	554	231↑	328	102↑
		323↓		226↓