Table 3. Univariate and multivariate linear regression of risk factors associated with liver stiffness measurement.
| Variables | Univariate analysis | Multivariate analysis | ||||
| β | Standard error | P-value | β | Standard error | P-value | |
| Entire CHB Cohort (n=330) | ||||||
| Age (years) | -0.124 | 0.577 | 0.024 | 0.070 | 0.026 | 0.169 |
| Sex | 0.058 | 0.028 | 0.295 | |||
| ALT (IU/L) | 0.353 | 0.008 | <0.001 | 0.241 | 0.009 | <0.001 |
| GGT (U/L) | 0.346 | 0.008 | <0.001 | 0.161 | 0.009 | 0.007 |
| ALP (U/L) | 0.171 | 0.011 | 0.002 | 0.041 | 0.011 | 0.430 |
| TB (μ/L) | 0.088 | 0.045 | 0.112 | |||
| TC(mmol/L) | -0.009 | 0.261 | 0.875 | |||
| BMI (kg/m2) | 0.264 | 0.081 | <0.001 | 0.097 | 0.101 | 0.147 |
| CAP (dB/m) | 0.28 | 0.008 | <0.001 | 0.116 | 0.010 | 0.085 |
| S0-1 CHB (n=227) | ||||||
| Age (years) | 0.036 | 0.022 | 0.590 | |||
| Sex | 0.005 | 0.426 | 0.937 | |||
| ALT (IU/L) | 0.299 | 0.008 | <0.001 | 0.209 | 0.008 | 0.004 |
| GGT (U/L) | 0.247 | 0.008 | <0.001 | 0.059 | 0.009 | 0.417 |
| ALP (U/L) | 0.055 | 0.009 | 0.412 | |||
| TB (μ/L) | 0.053 | 0.032 | 0.430 | |||
| TC (mmol/L) | 0.064 | 0.188 | 0.337 | |||
| BMI (kg/m2) | 0.274 | 0.060 | <0.001 | 0.103 | 0.079 | 0.227 |
| CAP (dB/m) | 0.323 | 0.006 | <0.001 | 0.179 | 0.008 | 0.041 |
| S2-4 CHB (n=103) | ||||||
| Age (years) | -0.003 | 0.066 | 0.979 | |||
| Sex | -0.229 | 1.391 | 0.020 | -0.140 | 1.393 | 0.152 |
| ALT (IU/L) | 0.289 | 0.015 | 0.003 | 0.203 | 0.016 | 0.050 |
| GGT (U/L) | 0.288 | 0.014 | 0.003 | 0.119 | 0.016 | 0.267 |
| ALP (U/L) | 0.095 | 0.026 | 0.338 | |||
| TB (μ/L) | 0.084 | 0.119 | 0.398 | |||
| TC (mmol/L) | -0.057 | 0.656 | 0.569 | |||
| BMI (kg/m2) | 0.277 | 0.191 | 0.005 | 0.140 | 0.239 | 0.246 |
| CAP (dB/m) | 0.217 | 0.019 | 0.028 | 0.092 | 0.023 | 0.436 |
ALT: alanine aminotransferase; GGT: gamma-glutamyl transferase; ALP, alkaline phosphatase; TB, total bilirubin; BMI, body mass index; CAP, controlled attenuation parameter; TC, total cholesterol