Table 1. Baseline characteristics of periodontitis patients and healthy individuals.
| Group Variables | Periodontitis (n=146) | Healthy (n=60) | P value1 |
| proBNP (ng/l) | 49.46 (± 63.07) | 35.33 (± 46.56) | = 0.002 |
| TpI (ng/l) | 3.30 (± 2.16) | 3.00 (± 0.00) | < 0.001 |
| CRP (mg/dl) | 0.11 (± 0.22) | 0.07(± 0.13) | = 0.160 |
| IL-6 (ng/l) | 1.60 (± 1.11) | 1.50 (± 0.00) | < 0.001 |
| β1AR-Aab2 (U/ml) | 17.12 (± 10.02) | 8.22 (± 5.13) | < 0.001 |
| β1AR-Aab3 (ng/ml) | 6.34 (± 2.55) | 2.31 (± 1.28) | < 0.001 |
| M5R-Aab2 (U/ml) | 24.14 (± 17.10) | 4.90 (± 3.04) | < 0.001 |
| Gender (% female) | 67.81 | 66.7 | > 0.99 |
| Age (years) | 47 (± 16.11) | 28 (± 11.66) | <0.0014 |
Median values of non-normally distributed data (± interquartile range)
1Significance of difference between groups
2IgG-binding to intact receptor
3IgG-binding to cyclopeptide representing the conformational auto-epitope within the second extracellular loop of the receptor
4Poor age-match of control group inevitable due to age-associated prevalence of periodontitis