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. 2020 Aug 27;12(16):16647–16662. doi: 10.18632/aging.103867

Table 1. Regulation of individual ATP synthase subunit protein expression levels across different tissue samples from different AD models, summarising data presented in this review.

Model Tissue α-subunit β-subunit OSCP Subunit d δ-subunit Reference
Aβ injected rat Hippocampus Down Shi, X. et al., 2011
SweAPP Tg mice Whole brain homogenate Up Carrette, O. et al., 2006
4 months old 5xFAD mice Synaptic mitochondria Down Beck, S. J. et al., 2016
9 months old 5xFAD mice Synaptic mitochondria Down Beck, S. J. et al., 2016
Non-synaptic mitochondria Down Beck, S. J. et al., 2016
3x Tg AD mouse Hippocampus Down Yu, H. et al., 2018
AD patient Temporal lobe Down Beck, S. J. et al., 2016
Medial frontal gyrus Down Adav, S. S. et al., 2019
Temporal cortex Down Mukherjee, S. et al., 2017
Frontal cortex Up Manczak, M. et al., 2004