Table 1. Correlation between KCNN4 expression and clinicopathologic factors in the TCGA cohort.
Clinicopathologic factors | Patients | High expression | Low expression | p-value |
Gender | ||||
Female | 367 | 180 | 187 | 0.546 |
Male | 135 | 71 | 64 | |
Age (years) | ||||
<60 | 389 | 196 | 193 | 0.831 |
≥60 | 113 | 55 | 58 | |
Histological type | ||||
Classical | 356 | 203 | 153 | <0.0001* |
Other types | 146 | 48 | 98 | |
Neoplasm focus type | ||||
Unifocal | 266 | 135 | 131 | 0.928 |
Multifocal | 226 | 113 | 113 | |
T stage | ||||
I+II | 307 | 135 | 172 | 0.001* |
III+IV | 193 | 114 | 79 | |
Lymph node metastasis | ||||
Yes | 222 | 150 | 72 | <0.0001* |
No | 229 | 83 | 146 | |
Disease stage(AJCC7) | ||||
I+II | 333 | 149 | 184 | 0.001* |
III+IV | 167 | 101 | 66 | |
New event | ||||
Yes | 44 | 27 | 17 | 0.155 |
No | 458 | 224 | 234 |
Note: *p-value< 0.05.
Abbreviations: KCNN4, Potassium calcium-activated channel subfamily N member 4; TCGA, The Cancer Genome Atlas; AJCC7, American Joint Committee on Cancer 7th edition.