Table 3. Thirty-six tag-SNPs in the target regions of IRF4, SCL24A4, TYR, and TYRP1.

Target gene	Tag SNP1	Frequency2 Brown (n = 16)	Frequency2 Blue (n = 24)	Captured variants (r2 ≥ 0.8)
IRF4	rs1050976	0.66	0.42	rs56116020, rs1050979, rs9378805, rs1050976, rs872071, rs9391997
	rs12211228	0.00	0.15	rs12211228, rs6906608
	rs10530949	0.78	0.52	rs2316515, rs10530949
	rs9378807	0.66	0.42	rs9378807
SLC24A4	rs10131374	0.03	0.19	rs10131374
	rs11160071	0.53	0.85	rs11160071, rs12435220, rs8008388, rs12883528, rs11623019, rs4904924, rs4904925, rs4904926, rs4904929
	rs12590749	0.09	0.42	rs12590749
	rs12880508	0.47	0.83	rs4904918, rs61977311, rs11160067, rs941648, rs3993878, rs10129711, rs10129728, rs10130041, rs4900124, rs12880508, rs11160069, rs7154848, rs9323877, rs7154400, rs4497611, rs4406992, rs10130373
	rs12894551	0.44	0.75	rs12894551
	rs17128288	0.53	0.19	rs4904896, rs28671668, rs17128288, rs10139051
	rs17128324	0.44	0.10	rs28668079, rs17128324, rs8019291, rs73339573, rs9323876
	rs34755843	0.31	0.13	rs117438089, rs34755843, rs78487705, rs78749625, rs61367228
	rs35617057	0.25	0.62	rs10594259, rs8015178, rs12894869, rs12895667, rs7142428, rs11621551, rs35617057, rs4410008, rs7143110, rs7144261, rs12881123, rs12882088, rs7143416
	rs4904887	0.16	0.37	rs4904887
	rs4904891	0.53	0.25	rs4243695, rs4904889, rs59778360, rs4243696, rs4904891, rs4904892, rs12435024, rs10139066, rs11624626, rs10142146, rs10142236, rs10142321, rs4900120, rs11443072, rs8010919, rs7150295, rs4414423, rs10143402, rs4603491, rs10431740, rs4904912, rs4904913
	rs4904897	0.38	0.15	rs4904897, rs11624887, rs4904903, rs11160063
	rs4904927	0.66	0.92	rs4904927, rs1998098
	rs59977926	0.03	0.31	rs59977926
	rs56007403	0.23	0.03	rs56007403, rs78863223, rs34608909
	rs7144273	0.37	0.67	rs7144273, rs7142789
	rs7152962	0.09	0.31	rs7152962, rs2402139
	rs7401792	0.41	0.69	rs7401792, rs12879396, rs7155002
TYR	rs2047512	0.09	0.33	rs2047512, rs2648640
	rs7120151	0.94	0.73	rs7120151, rs17184781
	rs34749698	0.06	0.25	rs7118021, rs67279079, rs34749698
	rs11018509	0.06	0.31	rs35702218, rs10765189, rs11018509 rs11018518, rs10830236, rs11018520, rs7949856, rs7925404, rs17791976, rs35486674, rs11018440, rs7103137, rs10830218, rs11018441, rs10830219
	rs1126809	0.03	0.29	rs1393350, rs72963135, rs1126809
	rs9919559	0.16	0.44	rs12273884, rs11018569, rs7947262, rs11018567, rs7924538, rs200640714, rs3907665, rs11018562, rs10830254, rs9919559, rs1827430, rs7951935, rs1806319, rs4121401
TYRP1	rs10491745	0.47	0.79	rs10491745, rs10756391
	rs1408799	0.37	0.71	rs1408799, rs1408800
	rs201447946	0.28	0.04	rs75001364, rs77306624, rs112446852, rs76579646, rs74874037, rs202148591, rs77448128, rs75611179, rs77494858, rs79586719, rs78774349, rs80287758, rs111589749, rs76969096, rs112201749, rs77445059, rs117687305, rs74889423, rs11791497, rs11787674, rs11791954, rs112923802, rs76988967, rs62638049, rs61758391, rs61758394, rs11787999, rs34509359, rs141808617, rs74606098, rs77446525, rs139301549, rs35866166, rs112342609, rs77990455, rs149076115, rs79662637, rs201447946, chr9:12703870, rs17280279, rs2209278, rs17280629, rs113819841
	rs74606098
	rs79586719
	rs2762457	0.31	0.60	rs2762457, rs10960748, rs10960749, rs13294134, rs10960751, rs10960752, rs13296454, rs59308154, rs2733831
	rs62538950	0.38	0.08	rs62538950, rs16929346, rs59334502, rs16929345
	rs62538956	0.41	0.10	rs144403042, rs62538954, rs62538956, rs62538957, rs62538946, rs79589462

¹The 36 tag-SNP captured 100% of the variants that showed association with eye colour (r² ≥ 0.8). Variants in italic are associated with categorical, but not quantitative eye colour.

²Frequency of variant.