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. 2020 Sep 11;15(9):e0238824. doi: 10.1371/journal.pone.0238824

Table 3. Cox proportional hazard model of adjusted overall survival (with selection from aGvHD, cGvHD, age, race, sex, disease, conditioning, KPS, HCT-CI, and donor type; significant level for entry = 0.1 and significant level for stay = 0.2, other variables are forced in the model) (N = 80, event = 53).

HR (95% CI) P-Value
Group
No Hepatic Steatosis -REF-
Hepatic Steatosis 0.57 (0.30–1.11) 0.10
Pre-transplant Weight (kg)
Continuous 0.95 (0.88–1.02) 0.17
Subcutaneous Fat
Continuous 1.00 (0.99–1.01) 0.43
Visceral Fat
Continuous 1.00 (0.99–1.01) 0.30
Skeletal Muscle Mass
Continuous 1.00 (0.98–1.02) 0.91
Age at Transplant
Continuous 1.04 (1.01–1.06) 0.003
Acute Graft vs Host Disease grade II-IV
No -REF-
Yes 2.903(1.47–5.74) 0.002
Chronic Graft vs Host Disease
No -REF-
Yes 0.43 (0.24–0.79) 0.007
HCT-CI
>3 -REF-
< = 3 0.44 (0.24–0.81) 0.008

HCT-CI: Hematopoietic Cell Transplantation-Comorbidity Index