Table 3. Cox proportional hazard model of adjusted overall survival (with selection from aGvHD, cGvHD, age, race, sex, disease, conditioning, KPS, HCT-CI, and donor type; significant level for entry = 0.1 and significant level for stay = 0.2, other variables are forced in the model) (N = 80, event = 53).
HR (95% CI) | P-Value | |
---|---|---|
Group | ||
No Hepatic Steatosis | -REF- | |
Hepatic Steatosis | 0.57 (0.30–1.11) | 0.10 |
Pre-transplant Weight (kg) | ||
Continuous | 0.95 (0.88–1.02) | 0.17 |
Subcutaneous Fat | ||
Continuous | 1.00 (0.99–1.01) | 0.43 |
Visceral Fat | ||
Continuous | 1.00 (0.99–1.01) | 0.30 |
Skeletal Muscle Mass | ||
Continuous | 1.00 (0.98–1.02) | 0.91 |
Age at Transplant | ||
Continuous | 1.04 (1.01–1.06) | 0.003 |
Acute Graft vs Host Disease grade II-IV | ||
No | -REF- | |
Yes | 2.903(1.47–5.74) | 0.002 |
Chronic Graft vs Host Disease | ||
No | -REF- | |
Yes | 0.43 (0.24–0.79) | 0.007 |
HCT-CI | ||
>3 | -REF- | |
< = 3 | 0.44 (0.24–0.81) | 0.008 |
HCT-CI: Hematopoietic Cell Transplantation-Comorbidity Index