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. 2020 Sep 11;15(9):e0238867. doi: 10.1371/journal.pone.0238867

Table 4. Incidence rate of hypophosphatemia and hypokalemia.

Hypophosphatemia Hypokalemia
IRR (95% CI) p-value IRR (95% CI) p-value
Group 2 vs. 1 1.14 (0.87–1.50) 0.698 Group 2 vs. 1 0.69 (0.39–1.20) 0.301
    3 vs. 1 0.45 (0.33–0.61) <0.001 3 vs. 1 0.50 (0.29–0.88) 0.010
    3 vs. 2 0.39 (0.29–0.53) <0.001 3 vs. 2 0.74 (0.41–1.33) 0.658
Age 1.00 (0.99–1.0) 0.550 Age 0.98 (0.97–0.99) 0.004
BMI 0.97 (0.95–0.99) 0.032 BMI 0.97 (0.92–1.01) 0.172
Female (vs. Male) 1.20 (0.99–1.45) 0.065 Female (vs. Male) 1.49(1.03–2.17) 0.034
APACHEII 1.0 (0.99–1.01) 0.772 APACHEII 0.99 (0.96–1.02) 0.451
GCS 1.0 (0.98–1.02) 0.792 GCS 1.08 (1.03–1.13) <0.001
Serum P_baseline 0.92 (0.88–0.96) <0.001 Serum K_baseline 0.53 (0.43–0.66) <0.001

IRR, incidence rate ratio; CI, confidence interval; RRT, continuous renal replacement therapy; APACHE II, Acute Physiology and Chronic Health Evaluation; GCS, Glasgow Coma Scale Hypophosphatemia is defined as serum phosphate was < 2.6 mg/dL, and hypokalemia as serum potassium was < 3.5 mmol/L.