Table 4. Factors of sensorineural hearing loss stratified by variables listed in the table by using Fine & Gray's competing risk model.
| With CKD | With CKD | With CKD vs. Without CKD (Reference) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Strarified | Events | PYs | Rate | Events | PYs | Rate | Wald | Adjusted HR | 95% CI | 95% CI | P |
| Overall | 368 | 334,193.43 | 110.12 | 960 | 1,168,647.66 | 82.15 | 303.22 | 3.42 | 3.01 | 3.90 | <0.001*** | |
| Gender | Male | 198 | 174,093.39 | 113.73 | 595 | 629,014.38 | 94.59 | 132.92 | 2.98 | 2.50 | 3.54 | <0.001*** |
| Female | 170 | 160,100.04 | 106.18 | 365 | 539,633.28 | 67.64 | 177.97 | 4.31 | 3.44 | 5.15 | <0.001*** | |
| Age groups (yrs) | 18–29 | 6 | 2,450.49 | 244.85 | 0 | 4,350.17 | 0.00 | 0.011 | ∞ | - | - | 0.897 |
| 30–39 | 6 | 8,722.15 | 68.79 | 5 | 15,192.58 | 32.91 | 2.266 | 3.37 | 0.77 | 14.82 | 0.724 | |
| 40–49 | 32 | 24,547.77 | 130.36 | 23 | 69,293.14 | 33.19 | 19.729 | 4.30 | 2.34 | 7.89 | <0.001*** | |
| 50–59 | 40 | 54,197.86 | 73.80 | 99 | 305,306.51 | 32.43 | 3.838 | 1.61 | 1.08 | 2.41 | 0.041* | |
| ≧60 | 284 | 244,275.16 | 116.26 | 833 | 744,505.26 | 111.89 | 278.74 | 3.67 | 3.18 | 4.23 | <0.001*** | |
| HTN | Without | 216 | 196,821.62 | 109.74 | 677 | 823,506.35 | 82.21 | 184.95 | 3.36 | 2.85 | 3.99 | <0.001*** |
| With | 152 | 137,371.81 | 110.65 | 283 | 345,141.31 | 82.00 | 121.14 | 3.67 | 2.95 | 4.62 | <0.001*** | |
| T2DM | Without | 244 | 226,763.67 | 107.60 | 782 | 902,618.82 | 86.64 | 196.28 | 3.24 | 2.77 | 3.77 | <0.001*** |
| With | 124 | 107,429.76 | 115.42 | 178 | 266,028.84 | 66.91 | 99.19 | 3.98 | 3.08 | 4.85 | <0.001*** | |
| HF | Without | 338 | 302,066.10 | 111.90 | 936 | 1,085,462.92 | 86.23 | 265.05 | 3.29 | 2.87 | 3.76 | <0.001*** |
| With | 30 | 32,127.33 | 93.38 | 24 | 83,184.74 | 28.85 | 38.87 | 7.48 | 4.08 | 13.78 | <0.001*** | |
| Stroke | Without | 329 | 303,790.75 | 108.30 | 793 | 1,031,091.16 | 76.91 | 270.73 | 3.48 | 3.03 | 4.02 | <0.001*** |
| With | 39 | 30,402.68 | 128.28 | 167 | 137,556.50 | 121.40 | 28.67 | 2.99 | 2.06 | 4.35 | <0.001*** | |
| COPD | Without | 342 | 313,272.56 | 109.17 | 830 | 1,024,602.66 | 81.01 | 275.41 | 3.39 | 2.96 | 3.90 | <0.001*** |
| With | 26 | 20,920.87 | 124.28 | 130 | 144,045.00 | 90.25 | 27.73 | 3.45 | 2.23 | 5.32 | <0.001*** | |
| Liver cirrhosis | Without | 344 | 317,482.25 | 108.35 | 915 | 1,108,300.52 | 82.56 | 280.16 | 3.39 | 2.97 | 3.88 | <0.001*** |
| With | 24 | 16,711.18 | 143.62 | 45 | 60,347.14 | 74.57 | 24.31 | 4.12 | 2.42 | 7.03 | <0.001*** | |
| Meniere's disease | Without | 356 | 331,468.23 | 107.40 | 834 | 1,131,989.89 | 73.68 | 308.07 | 3.58 | 3.13 | 4.10 | <0.001*** |
| With | 12 | 2,725.20 | 440.33 | 126 | 36,657.77 | 343.72 | 1.69 | 1.64 | 1.01 | 3.12 | 0.047* | |
| Aminoglycoside | Without | 366 | 332,526.32 | 110.07 | 953 | 1,161,049.27 | 82.08 | 137.94 | 3.41 | 3.00 | 3.92 | <0.001*** |
| With | 2 | 1,667.11 | 119.97 | 7 | 7,598.39 | 92.12 | 134.65 | 3.33 | 2.83 | 3.83 | <0.001*** | |
| Loop diuretics | Without | 367 | 331,401.74 | 110.74 | 957 | 1,157,557.93 | 82.67 | 138.02 | 3.42 | 3.00 | 3.93 | <0.001*** |
| With | 1 | 2,791.69 | 35.82 | 3 | 11,089.73 | 27.05 | 135.29 | 3.39 | 2.96 | 3.86 | <0.001*** | |
PYs = Person-years; Rate: per 100,000 PYs; Adjusted HR (hazard ratio): Adjusted variables listed in the table; CI = confidence interval
*P < 0.05, **P < 0.01
***P < 0.001