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. 2020 Sep 11;15(9):e0238182. doi: 10.1371/journal.pone.0238182

Table 5. Performance of selected comorbidity measures in assessing the association between comorbidity and selected outcome measures (Victoria).

Model Ln (ICU1 hours)2 Ln (MV3 hours)4 Number of complications5
Adjusted R2 Model fit AIC Adjusted R2 Model fit AIC Mc. Fadden's Adjusted R2 Model fit AIC
(i) Baseline model 0.104 14591 0.145 7815 0.029 106849
(ii) Baseline model + selected comorbidities (individually modelled with binary representation) 0.121 14498 0.164 7763 0.036 106142
(iii) Baseline model + selected comorbidities (modelled as a weighted summed score)6 0.121 14492 0.152 7795 0.032 106584
(iv) Baseline model + comorbidity using CCI weights 0.108 14572 0.147 7809 0.031 106639
(v) Baseline model + comorbidity using Quan weights 0.107 14577 0.147 7810 0.030 106720
(vi) Baseline model + ECM 0.130 14471 0.178 7752 0.036 106103

1. ICU–intensive care unit

2. Baseline model includes age, sex, injury severity, injury type and body region; outcome = ICU stay hours (Ln transformed linear model)

3. MV–mechanical ventilator

4. Baseline model includes age, sex and injury severity; outcome = MV hours (Ln transformed linear model)

5. Baseline model includes age, sex, injury type, injury severity and body region; outcome = number of complications for those with at least one complication (negative binomial model)

6. See Methods for weight calculation, excludes weights resulting from an odds <1.2, rounded weights used

See Table 6 for selected comorbidities for each outcome