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. 2020 Sep 11;14(9):e0008518. doi: 10.1371/journal.pntd.0008518

Fig 3. IgG1 responses to the S. mansoni antigens RP26, sm31, serpin, SEA and SWAP during S. mansoni infection and after the treatment.

Fig 3

Five mice were infected with 50 S. mansoni cercariae, and the sera were collected from five mice at each time point. A group of mice was orally treated twice with 500 mg/kg PZQ at 8 weeks post-infection. The experiment was repeated for 3 times and the representative data are presented. The means of the IgG1 level to the S. mansoni recombinant RP26 (A), sm31 (B), serpin (C), and crude SWAP (D) and SEA (E) are shown with the standard errors. The dashed line represents the cut-off value (mean + 3SD of the OD of the pre-infected group). IgG1 levels of the treated group (open diamonds) were compared with those of the untreated group (closed circles) and with those of pre-infection samples taken at week 0 (closed triangles). **p < 0.01 and ***p < 0.001.