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. 2020 Apr 13;13(5):972–984. doi: 10.1111/cts.12785

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© 2020 The Authors. Clinical and Translational Science published by Wiley Periodicals, Inc. on behalf of the American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Correlations among fecal omeprazole (OME), 5‐hydroxy (5‐OH) OME, and 5‐OH OME sulfide levels, and (a) alpha diversity (observed operational taxonomic unit (OTUs)) or (b) unweighted UniFrac distance to each subject’s baseline sample. Plots display regression lines for each individual subject and statistics displayed are from the repeated measures correlation using days 2–9. Subjects DM10 and DM18 were omitted as their study day 0 (baseline) samples were either below the sequencing quality threshold or not collected.