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Demographic and baseline characteristics of the PK population
| Variable | Children (n = 11) | Adolescents (n = 18) | All (n = 29) |
|---|---|---|---|
| Age a (years) | 9.0 (8–11) | 13.0 (12–16) | 12.0 (8–16) |
| Male, n (%) | 9 (81.8) | 13 (72.2) | 22 (75.9) |
| Nightly dosage a (mg/kg) | 150.0 (93–226) | 108.4 (70–184) | 112.4 (70–226) |
| Weight a (kg) | 43.0 (30–78) | 65.1 (39–129) | 60.0 (30–129) |
PK, pharmacokinetics.
Median (range).
