Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 31;16(8):e1008753. doi: 10.1371/journal.ppat.1008753

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Cottrell et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 1 — (A) Simplified immunization scheme as described in Sanders et al. 2015 [24]. Black arrows indicate i.m. immunizations with 100 μg of BG505 SOSIP.664 with 75 units of ISCOMATRIX adjuvant. Red arrows indicate blood draws. (B) Heavy and light chain genetic characteristics for mAbs isolated from rh1987 and rh2011. (C) TZM-bl neutralization of BG505.T332N, BG505.T332N.N611A, and SF162 pseudoviruses for mAbs isolated from RM rh1987. (D) TZM-bl neutralization of BG505.T332N, BG505.T332N.N611A, and SF162 pseudoviruses for mAbs isolated from RM rh2011. Assay limit of detection was at an IC₅₀ of 50 μg/mL.