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. 2020 Sep 11;15(9):e0238723. doi: 10.1371/journal.pone.0238723

Table 3. Logistic regression model for sleep medications and covariances.

Univariate analysis for fall OR (95%CI, P value) Multivariate analysis for fall OR (95%CI, P value)
Sleep medications use
Suvorexant 6.48 (3.66–11.7, <0.001) 2.61 (1.29–5.29, 0.008)
Ramelteon 2.41 (1.17–4.78, 0.013) 1.40 (0.60–3.16, 0.429)
Non-benzodiazepines 2.64 (1.95–3.56, <0.001) 2.49 (1.73–3.59, <0.001)
Benzodiazepines 1.71 (1.30–2.25, <0.001) 1.65 (1.16–2.34, 0.005)
Kampo (yokukansan) 3.37 (1.85–6.06, <0.001) 1.55 (0.75–3.19, 0.233)
Department
Orthopaedic surgery (Reference)
Internal medicine 0.46 (0.34–0.63, <0.001) 1.19 (0.81–1.77, 0.367)
General surgery 0.56 (0.33–0.89, 0.019) 1.75 (0.93–3.17, 0.074)
Rehabilitation 2.10 (1.36–3.21, <0.001) 1.20 (0.69–2.06, 0.510)
Others(Gynecology, Urology, Dermatology, Psychology) 0.42 (0.16–0.92, 0.047) 1.42 (0.48–3.52, 0.481)
Hospitalized duration (per 1day) 1.031 (1.027–1.035, <0.001) 1.024 (1.020–1.029, <0.001)
Fall down risk score (per 1point) 1.18 (1.15–1.21, <0.001) 1.15 (1.11–1.19, <0.001)

Multiple logistic regression adjusted age, sex, all sleep medications, department, hospitalized duration, fall down risk score.

OR: odds ratio, CI: confidence interval.