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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Bone Miner Res. 2020 Jun 5;35(9):1798–1811. doi: 10.1002/jbmr.4029

Figure 1. Fak deletion in Dermo1-expressing cells leads to osteopenia in mice.

Figure 1.

MicroCT analysis were performed in femurs of 2-month-old male Fakflox/flox (Control), Fakflox/+;Dermo1-Cre (CHet) and Fakflox/flox;Dermo1-Cre (CKODermo1) mice. (A-E) Femoral trabecular bone: (A) Representative microCT image, scale bar=500 μm; (B) BV/TV, bone volume fraction; (C) Tb.N, trabecular number; (D) Tb.Th, trabecular thickness; (E) Tb.Sp, trabecular spacing. (F-J) Femoral cortical bone: (F) Representative microCT image, scale bar=300 μm; (G) Tt.Ar, total cross-sectional area inside the periosteal envelope; (H) Ma.Ar, marrow area; (I) Ct.Ar, cortical bone area; (J) Ct.Th, average cortical thickness. Values were presented as median and interquartile range (n=8 for control group, n=9 for CHet group, and n=9 for CKODermo1 group).