Fig. 8.

Eradication effects of different concentration of chelerythrine on mono- and dual-species of S. aureus ATCC 25,923 and S. lugdunensis ATCC 700,328 mature biofilms. a The relative biomass of biofilm was assessed using crystal violet staining assay. Values represent the means of triplicate measurements. Bars represent the standard deviation (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001; NS, not significant. b, c, d ESEM images of mono- and dual-species of S. aureus ATCC 25,923 and S. lugdunensis ATCC 700,328 mature biofilms after treatment with four concentrations of CHE (scale bar: 10 μm). Each field of vision was magnified 10 000 ×