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. 2020 Sep 6;31:100605. doi: 10.1016/j.ijcha.2020.100605

Table 1.

Baseline characteristics between Low and Intermediate/High bleeding risk groups.

Low Bleeding Risk
N = 1270
Intermediate to High Bleeding Risk
N = 1009
P-value
Age, years 61.4 ± 10.1 70.5 ± 10.3 <0.0001*
Females 251(19.8%) 288(28.5%) <0.0001*
Race 0.011
  • Asian

263(21.1%) 188(18.9%)
  • Black

7(0.6%) 2(0.2%)
  • Other

59(4.7%) 26(2.6%)
  • White

919(73.6%) 779(78.3%)
BMI (kg/m2) 28.8 ± 3.6 27.1 ± 5.8 <0.0001*
BMI < 25 kg/m2 108(8.5%) 483(47.9%) <0.0001*
Diabetes mellitus 398(31.3%) 320(31.7%) 0.85
  • Insulin

84(22.5%) 88(29.0%) 0.06
Current smoker 250(19.7%) 391(38.8%) <0.0001*
Hypercholesterolemia 762(60.0%) 588(58.3%) 0.41
Hypertension 900(70.9%) 726(72.0%) 0.57
Congestive heart failure 69(5.4%) 102(10.1%) <0.0001*
Chronic renal failure 11(0.9%) 140(13.9%) <0.0001*
Peripheral arterial disease 47(3.8%) 85(8.6%) <0.0001*
Previous stroke 43(3.4%) 62(6.1%) 0.0018*
Previous MI 312(24.6%) 228(22.6%) 0.27
Previous PCI 325(25.6%) 270(26.8%) 0.53
Previous CABG 66(5.2%) 63(6.2%) 0.28
Atrial fibrillation 42(3.4%) 130(13.2%) <0.0001*
Medications on Admission
  • ACE inhibitors or ARB

747(58.8%) 577(57.2%) 0.43
  • Beta-blockers

735(57.9%) 555(55.0%) 0.17
  • Anticoagulation

23(1.8%) 108(10.7%) <0.0001*
  • Statins

921(72.5%) 663(65.7%) 0.0005*
  • Proton pump inhibitor

422(33.2%) 400(39.6%) 0.0015*
  • Aspirin

886(69.8%) 642(63.6%) 0.0020*
Discharge medications
  • ACE inhibitors or ARB

957(75.4%) 745(73.8%) 0.41
  • Beta-blockers

977(76.9%) 754(74.7%) 0.22
  • Anticoagulation

38(3.0%) 151(15.0%) <0.001
  • Statins

1226(96.5%) 940(93.2%) 0.0002
  • Proton pump inhibitor

589(46.4%) 570(56.5%) <0.001
  • Aspirin

1262(99.4%) 989(98.0%) 0.004
  • P2Y12 inhibitor

0.0001
  • -

    Clopidogrel

830(65.4%) 737(73.0%)
  • -

    None

0(0.0%) 4(0.4%)
  • -

    Prasugrel

52(4.1%) 24(2.4%)
  • -

    Ticagrelor

385(30.3%) 243(24.1%)
  • -

    Ticlopidine

3(0.2%) 1(0.1%)

Values are shown as n (%) or mean ± standard deviation (SD). ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; BMI, body mass index; CABG, coronary artery bypass grafts; MI, myocardial infarction; PAD, peripheral arterial disease; PCI, percutaneous coronary intervention.