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Migration effect of plant-produced hEGF on HaCaT cells (A) Relative migration after 12 and 24 h treatment with 50, 100 ng/mL of plant-produced EGF (P-EGF) and commercial hEGF (hEGF-control). The data was presented as mean ± SD; * indicates a significant difference of relative migration level between treated cells and untreated cells at p ≤ 0.05. (B) The closure of wound area was observed at 12 and 24 h after treatment with 50, 100 ng/mL of plant-produced and commercial hEGF.
